The Validation Study of Otoacoustic Emission by the Regulation of Body Temperature in the Mouse Model
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서지정보
ㆍ발행기관 : 한국청각언어재활학회
ㆍ수록지정보 : 청능재활 / 3권 / 2호
ㆍ저자명 : Bin-Na Hong, Tae-Gyu Park, Tong-Ho Kang
ㆍ저자명 : Bin-Na Hong, Tae-Gyu Park, Tong-Ho Kang
목차
INTRODUCTIONMATERIALS AND METHODS
RESULTS
DISCUSSIONS
REFERENCES
한국어 초록
Objective:The otoacoustic emission (OAE) is a useful method for evaluating cochlear function. The aim of this study is the validation of TEOAE (transiently evoked otoacoustic emission) and DPOAE (Distortion product otoacoustic emissions) by the regulation of a body temperature in the mouse model. Method:Adult male ICR mice 7 weeks were used in this study. OAE test were performed according to body temperature at 34℃, 37℃ and 40℃ respectively. TEOAE and DPOAE were recorded using a CAPELLA (MADSEN) in the mouse. Results:In OAE test for the optimization of body temperature, the intensity of TEOAE andDPOAE was the lowest at 40℃ and the highest at 37℃, but no significantly difference. The 4 kHz DPOAE threshold of normal temperature was the lowest. The results suggest that the OAE for cochlear function test keep optimal body temperature for good reliable results in the mouse.
KEY WORDS:Transiently evoked otoacoustic emission (TEOAE)·Distortion product otoacoustic emissions (DPOAE)· Body temperature·Mouse model.
영어 초록
Objective:The otoacoustic emission (OAE) is a useful method for evaluating cochlear function. The aim of this study is the validation of TEOAE (transiently evoked otoacoustic emission) and DPOAE (Distortion product otoacoustic emissions) by the regulation of a body temperature in the mouse model. Method:Adult male ICR mice 7 weeks were used in this study. OAE test were performed according to body temperature at 34℃, 37℃ and 40℃ respectively. TEOAE and DPOAE were recorded using a CAPELLA (MADSEN) in the mouse. Results:In OAE test for the optimization of body temperature, the intensity of TEOAE andDPOAE was the lowest at 40℃ and the highest at 37℃, but no significantly difference. The 4 kHz DPOAE threshold of normal temperature was the lowest. The results suggest that the OAE for cochlear function test keep optimal body temperature for good reliable results in the mouse.KEY WORDS:Transiently evoked otoacoustic emission (TEOAE)·Distortion product otoacoustic emissions (DPOAE)· Body temperature·Mouse model.참고 자료
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