GH Increases the Progesterone at Peri-estrus Stage in Mice Co-injected with PMSG for Superovulation

서지정보

ㆍ발행기관 : 한국동물번식학회 ㆍ수록지정보 : Reproductive & developmental biology / 35권 / 4호
ㆍ저자명 : Young Gee Kim, Zae Young Ryoo, Young Sik Park

목차

ABSTRACT INTRODUCTION MATERIALS AND METHODS Experimental Animals and Housing Conditions Superovulation Treatment GH Treatment Estrus Evaluation Pregnancy Evaluation Analysis of Serum P4 and E2 Statistical Analysis RESULTS GH and Reproductive Traits in Superovulation-Induced Mice GH and Serum E2 and P4 Levels in Superovulation-Induced Mice GH and Steroids at Peri-Estrus Stage GH and Steroids at Peri-Ovulation Stage GH and Steroids at Peri-Implantation Comparison of PMSG and PMGS+GH superovulation systems GH and Fetus Number in Superovulated Mice DISCUSSION GH and Estrus in Superovulation-Induced Mice GH and Pregnancy in Superovulation-Induced Mice REFERENCES

영어 초록

Growth hormone (GH) is obligatory for growth and development. But, there is controversy on the GH effect about reproductive processes of sexual differentiation, pubertal maturation, gonadal steroidogenesis, gametogenesis and ovulation. This study was conducted to investigate the effect of GH on estrus, ovulation and embryo implantation. The results obtained were as follows. GH stimulated to increase estrus rate (p<0.05), pregnancy rate (p<0.05), and total fetus number in mice treated for superovulation. Also, the correlation between GH and steroids, E2 and P4, at peri-estrus stage/ peri-ovulation stage/ peri-implantation stage of the superovulation-induced mice was examined. Consequently, GH co-injected with PMSG especially increased P4 level (p<0.05) at peri-estrus stage of superovulationinduced mice. In conclusion, GH co-treatment in superovulation system boosted the rate of estrus, pregnancy and total fetus by increasing progesterone level at peri-estrus stage of superovulation-induced mice.

참고 자료

없음