The preparation of skin analogue composition having the liquid crystalline structure and its cosmetic applications
* 본 문서는 배포용으로 복사 및 편집이 불가합니다.
서지정보
ㆍ발행기관 : 한국유화학회
ㆍ수록지정보 : 韓國油化學會誌 / 30권 / 2호
ㆍ저자명 : Dong-Kyu Lee, Kwan-Young Jeong
ㆍ저자명 : Dong-Kyu Lee, Kwan-Young Jeong
영어 초록
Recently, many cosmetic researchers have been focused on the development of high functional cosmetics including anti-wrinkle and whitening. In these studies, they couldn't afford to pay a deep attention to stable encapsulations for unstable materials and efficient drug deliveries for them. Particularly, in order to show a degree of instant effects as cosmetics, they can't also ignore moisturizing effect enough to satisfy customers just after applying and its maintenance by improving the function of skin barrier as well as above two effects. Therefore, skin analogue systems have attracted considerable attention in the view of structural and compositional similarity to intercellular membrane in stratum corneum. And, some models for skin analogue composition were developed to improve the function of skin barrier, stably encapsulate unstable materials such as retinol, vitamin B, C, E, etc., and control their skin penetration in order to show good effects as cosmetics. In this study, we suggest the new skin analogue model having the compositional similarity as well as conventional structural ones. Our skin analogue membrane(SAM) is mainly composed of ceramide/ cholesterol/phosphatidylcholin/fatty acids and its structural defects are compensated by including cholesterol amphiphile and controlling the ratio of ceramide/cholesterol. It was possible to confirm the formation of skin analogue membrane having highly-densed multilamella structure and compare them according to the change of each ratio with a polarized microscope, X-ray diffraction. More detaily, we observed their structures with a electron microscope(TEM). Finally, we dispersed them in excess of continuous water phase, observed the formation of maltese-cross liquid crystalline and measured the efficiency of drug deliveries and moisturizing effects.참고 자료
없음태그
"韓國油化學會誌"의 다른 논문
태백시 소각로 내 NOx 제거를 위한 전산유체역학(CFD) simulation 연구13페이지
2-메틸숙신산을 이용한 에스테르계 제미니 양이온 계면활성제의 합성 및 물성8페이지
Biomass-based 고분자 블렌드 필름의 제조 및 특성 연구(2)7페이지
GMA와 프탈이미드아크릴레이트의 공중합체 합성과 반응성비8페이지
Comparative Study on Interfacial Traps in Organic Thin-..7페이지
Phosphate ester 계면활성제를 이용한 다중층 라멜라 베시클의 제조 및 특성10페이지
발효보이차 추출물의 항산화활성 및 보습효과8페이지
Monoamonium Phosphate를 이용한 수분산 폴리우레탄 수지의 합성과 물성에 관한 연구8페이지
화학센서를 위한 유기 용해성이 좋은 도전성 고분자가 포함된 전체 고체상태 이온 선택성 전극에 대한 ..6페이지
L-α-Phosphatidylcholine 매질에서 빔산란에 의한 Methotrexate의 측정7페이지