prognosis of CSS (Churg-Strauss syndrome)
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- 2009.05.30
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- 2008.01
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prognosis of CSS (Churg-Strauss syndrome) 레포트
목차
Prognosis
five-factor score or FFS
Treatment
Reference
본문내용
Prognosis
Untreated 5-year survival rate : 25%
Treated 78-month actuarial survival rate : 72%
Myocardial involvement : most frequent cause of death, responsible for 39%
five-factor score or FFS
(1) reduced renal function (creatinine >1.58 mg/dL or 140 μmol/l)
(2) proteinuria (>1 g/24h)
(3) gastrointestinal hemorrhage, infarction or pancreatitis
(4) involvement of the central nervous system
(5) cardiomyopathy
Presence of 1 of these indicates severe disease (5-year mortality 26%)
2 or more indicates very severe disease (mortality 46%)
absence of any of these 5 indicates a milder case (mortality 11.9%)
참고 자료
Harrison’s principle of Internal Medicine, 16th edition
Guillevin L, Lhote F, Gayraud M, et al (1996). Prognostic factors in polyarteritis nodosa and Churg-Strauss syndrome. A prospective study in 342 patients. Medicine (Baltimore) 75 (1): 17–28
Bosch X, Guilabert A, Espinosa G, Mirapeix E (2007). Treatment of antineutrophil cytoplasmic antibody associated vasculitis: a systematic review. JAMA 298 (6): 655–69
