결핵의 영상학적 소견 진단 치료

소개글

TB 에 관한 PPT 입니다

내과 인턴 돌며 만든 것이며 영상 및 조직 소견(x-ray 및 CT AFB stain 등등)

그림 좋은거 많이 담겨 있습니다

목차

Introduction

Definition

Latent TB

Active TB

Clinical symptoms

Diagnosis

Diagnosis Chest x-ray

Diagnosis chest CT

Diagnosis AFB stain

Diagnosis - Culture

Diagnosis - PCR

Diagnosis Mantoux skin test

Diagnosis Interferon-r assay

Treatment

본문내용

Introduction
Definition
Caused by Mycobacterium tuberculosis complex
Lung is the major site for M. tuberculosis infection
Transmitted through the air borne spread of droplet
A rod-shaped, thin aerobic bacterium
*
Active vs Latent TB
Latent TB
Remains in an inactive state after infection
No symptoms
Not contagious
Active TB
With symptoms
Contagious
Cell mediated immunity is the most deterministic factor
(Macrophage & CD4- T lymphocyte)
10% of Latent TB will eventually develop active TB




Diagnosis Interferon-r assay
QuantiFERON-TB test
Aid in the diagnosis of TB infection
Over night incubation of peripheral blood with PPD
Measurement of IFN-r released by sensitized lymphocyte
Screening for TB infection at low to moderate risk population
Sensitivity & Specificity is not known
*
Treatment
First line
Isoniazid (INH)
Ethambutol (EMB)
Rifampicin (RMP)
Pyrazinnamide (PZA)
Streptomycin (STM)
Second line
Aminoglycosides (AMK)

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