위암

소개글

말이 필요없는 자료! 대한민국 암 발병률 1위! 그 만큼 완치율도 높은 위암입니다. 위암도 대장암과 마찬가지로 2010 TNM stage가 소폭 개정되었습니다. 그에 대한 내용과 요즘 늘어나고 있는 GIST등 위에 생기는 암에 대해 간략하게 의과대학생 수준에서 정리하였습니다. 가장 최신 지견으로 도움이 많이 될 것입니다. NCCN 가이드라인 이 기본내용입니다.

목차

Epidemiology
Etiological Factors of Gastric Cancer
Diagnosis
Classification
Clinical menifestation-Sx.
Clinical menifestation-P/E
Staging(AJJC seventh edition)
Treatment
Surgical treatment
Adjuvant chemotherapy
Neoadjuvant chemotherapy
Combination chemotherapy
Prognosis
Primary gastric lymphoma
Gastric sarcoma
Gastrointestinal stromal tumor
Reference

본문내용

Etiological Factors of Gastric Cancer

The development of gastric cancer is a multi-factor process. A large number of risk factors have been associated with gastric cancer. These include dietary factor, smoking, H. pylori infection, low gastric acidity, genetic factors. Excessive intake of salt or salty food, low consumption of fresh fruits and vegetables are likely contribute to the development of gastric cancer. Studies had indicated there was a significant association between cigarette smoking and gastric cancer risk, particularly in male smokers. H. pylori is a definite carcinogen accounting for at least 300 000 new cases of gastric cancer each year worldwide. Familiar studies have found that the risk of developing gastric cancer for relatives of cases is increased two- to three-fold suggesting a role of genetic factors. Low gastric acidity may increase intraluminal formation of N-nitroso compounds which are carcinogens.

참고 자료

Harrison’s Internal medicine, 17th edi., 570-580

NCCN Clinical Practice Guidelines in Oncology™, Gastric Cancers

Valle J. et al.(2010), N Engl J Med 2010;362:1273-81

Primary gastric lymphoma, Ahmad M. Al-Akwaa, Neelam Siddiqui, Ibrahim A. Al-Mofleh

European consensus conference recogmendations& NCCN sarcoma guideline 2005