면역글로불린의 종류와 기능

소개글

면역글로불린의 종류와 기능에 대한 레포트입니다.

목차

1. Immunoglobulin
2. Immunoglobulin의 종류와 기능

본문내용

1. Immunoglobulin
▷ Antibody
- 혈장, 림프, 조직액 등의 체액에 존재하여 체액성 (humoral immune response)을 매개하는 면역글로불린(immunoglobulin) 단백질
- B 림프구가 분화한 형질세포(plasma cells)에 의해 생산되는 당단백질
▷ Two separable functions: (antigen recognition / effector function)
- To bind specifically to molecules from the pathogen that elicited the immune response; Ag-binding region
- To recruit other cells and molecules to destroy the pathogen once the antibody is bound to it ; Region for effector mechanisms; Constant region
▷ Antigen Neutralization
- Neutralization of toxins
- Neutralization of viruses and bacteria to prevent their attachment to cell receptors
▷ Opsonization (IgG)
- Promotion of phagocytosis of antigens by macrophages and neutrophils
- Protein molecules called Fc receptors (FcR), which bind the constant region of antibody are present on the surfaces of phagocytes.

참고 자료

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