Fluoxetin, Prozac 관련 조사 레포트
- 최초 등록일
- 2012.11.26
- 최종 저작일
- 2012.01
- 22페이지/ 한컴오피스
- 가격 2,000원
소개글
해외 논문 사이트 참조한 fluxetin 보고 레포트
목차, 각주, 다양한 그림 등 깔끔하게 정리되어 있음.
위키피디아 검색 이상의 심화 내용
목차
1.fluoxetine
2.background mechanism
3.Discovery & Development
4.Pharmacokinetics and pharmacology
5.Properties
6.Synthesis
본문내용
1.Fluoxetine
1.1 Fluoxetine
Fluoxetine (also known by the tradenames Prozac?, Sarafem?, Fontex?, among others) is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. Fluoxetine was first documented in 1974 by scientists from Eli Lilly and Company. It was presented to the U.S. Food and Drug Administration in February 1977, with Eli Lilly receiving final approval to market the drug in December 1987. Fluoxetine went off-patent in August 2001. Fluoxetine is approved for the treatment of major depression (including pediatric depression), obsessive-compulsive disorder (in both adult and pediatric populations), bulimia nervosa, panic disorder and premenstrual dysphoric disorder. In addition, fluoxetine is used to treat trichotillomania if cognitive behaviour therapy is unsuccessful. In combination with olanzapine it is known as Symbyax. Despite the availability of newer agents, fluoxetine remains extremely popular. In 2010, over 24.4 million prescriptions for generic formulations of fluoxetine were filled in the United States alone,[4] making it the third most prescribed antidepressant after sertraline (SSRI; became generic in 2006) and citalopram (SSRI; became generic in 2003).
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Altered anti-coagulant effects (laboratory values and/or clinical signs and symptoms), with no consistent pattern, but increased bleeding, have been reported uncommonly when PROZAC 20 is co-administered with warfarin. As is prudent in concomitant use of warfarin with many other medicines, patients receiving warfarin therapy should receive careful monitoring when PROZAC is initiated or stopped.
5.6.5 Electroconvulsive therapy (ECT)
There have been rare reports of prolonged seizures in patients on PROZAC 20 receiving ECT treatment
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