당뇨병과, 그에 따른 치료책인 pancreatic development from iPS cell
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- 2012.12.17
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- 2012.11
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당뇨병과, 그에 따른 치료책인 pancreatic development from iPS cell에 관한
발표자료 ppt입니다
목차
1. Intro
2. Analysis
3. Discussion
본문내용
Type 2 diabetes mellitus (T2DM)
~90% of total diabetes population
Resistant to insulin in target tissues
Reduced insulin secretion resulting from pancreatic β-cell failure lead to functional β-cell alterations and loss of β-cell mass by apoptosis
Therapy : Exercise, Weight loss, Low-carbohydrate diet, Insulin injection
β-cell transplantation → Permanent treatment
→Temporary treatment
The major obstacle is the limited source of insulin-producing cell
<중 략>
Flow cytometry
Used for cell counting, sorting, biomarker detection
by suspending cells in a stream of fluid and passing them by an electronic detection apparatus.
It allows multiparametric analysis of the physical, chemical characteristics among thousands of other particles.
<중 략>
1.Earlier Mistake
Insulin immunohistochemistry
-possibility uptake from medium
Selection of cells mistake
-misusage nestin
Overcome(Present)
-measurement of C-peptide
-detect sequence marker
참고 자료
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