급성호흡곤란증후군 요약

목차

1. 요약
2. 기전
3. 정의와 원인
4. 임상경과
5. 치료

본문내용

1.요약
Course for the development and resolution of ARDS.
The exudative phase is notable for early alveolar edema and neutrophil-rich leukocytic infiltration of the lungs with subsequent formation of hyaline membranes from diffuse alveolar damage.
Within 7 days, a proliferative phase ensues with prominent interstitial inflammation and early fibrotic changes. Approximately 3 weeks after the initial pulmonary injury, most patients recover.
However, some patients enter the fibrotic phase, with substantial fibrosis and bullae formation.

<중 략>

- Goal: PaO2 60mmHg, SaO2 90%
- O2: 산소독성 예방 위해 FiO2<0.6 (처음엔 1.0에서 시작해서 0.6으로 점점감소시킴)
- mechanical ventilation: low tidal volume(6ml/kg)
- 기도내압의 최대치는 30-35mmHg가 넘지 않도록한다
- PEEP : 적응- PaO2를 60mmHg이상 유지하기 위해 FiO2가 0.6이상 필요시
목적- 낮은 FiO2로 적절한 PaO2유지
효과★- alveolar collapes open, shunt 감소, Work Of Breathing 감소
FRC증가, lung compliance증가

참고 자료

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