hypothese first
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- 2013.07.14
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first or Data first?
Written by Kang Jun gu
Cancer is big theme for human death. All cancer occurs as a result of changing DNA sequence of the genome of cancer cells. It follows two processes, analogous to Darwinian evolution as natural selection and random mutation. In the process, autonomous barrier in the body could limit the majority of proliferation of cancer but some cell get a set of mutations to invade tissues and metastasize.
Like all the cells, a cancer cell follows a lineage of somatic mutation. Most of damage is repaired in the cells as you know, but some mutagens; carcinogens, viral infections, radiation s and so on could be accumulated and mutation rate could be larger and higher. Finally, cancer cell gets ability to resist chemotherapy.
<중 략>
So, it’s the first thing to grasp the entire network of cancer genome. Recently, some trials are reported to make international cancer genome consortium, abbreviated as ICGC. The goals of ICGC are to coordinate large-scale cancer genome studies in tumors from 50 different cancer types and subtypes that are of clinical and societal importance across the globe. It will ensure high quality by defining the catalogue for each tumor type and make the data available to the entire research community as rapidly as possible. As you expect, the researches for cancer genomics will speed up and lots of trials for connecting data each other will be successful.
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