Antibacterial compounds from microorganism

목차

1. Introduction
2. Conventional assay methods
3. Radioimmuno assay
4. ELISA(Enzyme-linked immunosorbent assay)
5. Target-Directed Screening
6. Beta-lactam계 항생제
7. Aminoglycoside antibiotics
8. Conclusion
9. antibiotics and their properties

본문내용

Introduction
Penicillin : discovered by Fleming in 1928, and in the same year, Waksman started the screening of antibacterial substance by a soil actinomycete, and discovered the actinomycins.
Some of a used as antumor agent.

Conventional assay methods
1)Use of antibiotic-resistant mutants
enzyme inhibition or blocking of transport systems also have been taken into consideration.
Staphylococcus aureus 4R, S.aureus FDA209A = resistant to tetracycline, erythromycin, chloramphenicol, and streptomycin 2,000 actinomycete strains were tested, a new dipeptide antibiotic named alahopcin was found.

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