Necrotizing fascitis, 괴사성 근막염
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소개글
Necrotizing fascitis, 괴사성 근막염
헤리슨(내과총론) 18판에 나와 있는 Necrotizing fascitis 내용을 모두 담았습니다.
원인, 병태생리, 증상, 진단, 치료에 관한 내용을 모두 실었으며 Harrison을 기반하여 모두 작성하였습니다.
Necrotizing fascitis를 이해하는데에 전혀 문제되지 않을 것입니다.
목차
1. 원인
2. 병태생리
3. 증상
4. 진단
5. 치료
본문내용
streptococcal gangrene, associated with group A streptococcus(S. pyogens, or mixed aerobic- anaerobic or part of gas gangrene cause of Clostridium perfringens.
Strains of MRSA that produce the panton-Valentine leukocidin toxin have been reported to cause necrotizing fascitis
<중 략>
Early and aggressive surgical exploration is essential in cases of suspected necrotizing fasciitis
Appropriate empirical antibiotic treatment for mixed aerobic-anaerobic infections could consist of ampicillin/sulbactam, cefoxitin, or the following combination:
(1) clindamycin (600-900 mg intravenously eveα 8 h) or metronidazole (500 mg every 6 h) plus
(2) ampicillin or ampicillin/sulbactam (1.5-3 g intravenously every 6 h) plus
(3) gentamicin (1-1.5 mg/kg every 8 h).
Necrotic tissue must be surgically removed, and Gram's staining and culture of excised tissue are useful in establishing whether group A streptococci, mixed aerobic-anaerobic bacteria, MRSA, or Clostridium species are present.
참고 자료
Harrison's Principles of Internal Medicine 18th edition