b cell 발표 수정본

목차

1. B cells
2. B cell receptors
3. Diversity
4. Immunoglobulins
5. Development
6. Pre B cell receptor

본문내용

Kinds of secondary lymphoid organ
: lymph node, spleen, GALT(Peyer's patch), MALT, BALT..
Immature B cell to leave the bone marrow to enter the secondary lymphoid organ.

5. Mature Bcell
① Attract of B cell ( to lymph node)
: lymph node cortex- stroma cell → cytokine CC21
lymph node- dendritic cell → cytokine CC21, CC19
② Attract of B cell ( to primary lymphoid follicles)
: FDC(follicular dendritic cell) → chemokine CXCL13
③ Mature of immature B cell (in primary lymphoid follicles) : Lymphotoxin, BAFF
④ In the absence of B cell antigen is separated from the FDC to circulate through the efferent lymph leaving a lymph node. → mature B cell

참고 자료

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