[case review] 소화기내과_gastric cancer

목차

1. Introduction & Etiology
2. Classification: Anatomical
3. Classification: Histological (Lauren classification)
4. Classification: Histological (WHO classification
5. Classification: Molecular
6. Symptoms & Diagnosis
7. Surgical Treatment
8. Management of locally advanced diseas
9. Management of metastatic disease

본문내용

Introduction & Etiology
• 4th most common cancer
• 2nd leading cause of cancer death

• H . p y l o r i
infection: most important cause of sporadic distal gastric cancer
• Chronic inflammation + various factors
• Gastric atrophy → Intestinal metaplasia → dysplasia & adenocarcinoma
• Epstein-Barr virus: role remains unclear
• Hereditary: 1-3%
• Hereditary diffuse gastric cancer: C D H 1 mutation (40%), C T N N A 1 mutation
• Gastric adenocarcinoma & proximal polyposis of the stomach
• Familial intestinal gastric cancer
• Enviromental: fruits/vegetables ↓, salt/nitrate/pickled food↑, smoking, obesity,

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Symptoms & Diagnosis
• Early stage: Asymptomatic
• Symptoms: Anorexia, dyspepsia, weight loss, abdominal pain
• Diagnosis: Endoscopy + Biopsy

참고 자료

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