biomechanics of sckeletal muscle

소개글

"biomechanics of sckeletal muscle"에 대한 내용입니다.

목차

1. Structure of skletal muscle

2. Non-contractile components of muscle
2-1 Intracellular protein
2-2 Extracellular matrix(주로 아교질과 탄력소로 구성)


3. Factors that infuence a muscle’s ability to produce a motion
3-1 effect of fiber length on joint excursion
3-2 architecture of skeletal muscle
3-3 Muscle size and its effect on force production
3-3 Relationship between force production and instantaneous muscle length( stretch)
3-4 Relationship between a muscle’s moment arm and its force production

4. Relationship between force production and level of recruitment of motor units within the muscle

5. Relationship between force production and motor unit type

본문내용

1.Structure of skletal muscle
-skeletal muscle 은 bone과 muscle을연결해주는 tendon에 muscle belly가연결되어있는구조
-Muscle fiber는 myofibril로구성
-myofibril의한마디는 sarcomere로구성
-sarcomere는 myofilament( actin filament / myosin filament) 로구성
-Myosin 머리위에서 actin filament가결합하여 actin이밀려들어가면서수축이나타는것을 cross-bridge라함.
-근수축현상은 muscle fiber의전기적자극으로탈분극이일어나면서시작한다.

2. Non-contractile components of muscle
-근섬유들의안과사이에서세포뼈대를구성. 근섬유들의구조를지지역할
=> 구조단백질 : 수축은직접하지않지만힘전달에있어중요한 2차적역할을함.

2-1 Intracellular protein
-Titin : 큰단백질 , muscle fiber의 passive stiffness에기여한다고함.
-Desmin : Z - disc에존재하는 filament, myofilament의안정성에기여함.
결손시 muscle weakness와손상과연관되어있음.
- costameres : superficial sarcomeres를세포벽에연결시키는단백질복합체의세포질을안정시키고, 세포벽과 extracellular matrix의기저막에연결시킴으로써근섬유지지에도움을준다.

일반적으로수동단백질은특성
1)신장될때수동장력발생
2)근섬유의내외적안정성
3)해당근육내에서발생한능동적힘들을전달할때도움

2-2 Extracellular matrix(주로아교질과탄력소로구성)
Muscle belly를 muscle cell과(또는) fiber & connective tissue 로알려진 ECM으로구성됨.ECM은 connective tissue로구성된세가지시스템으로묘사됨.

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