소개글
"Hirschsprung's disease(히르쉬스프룽병)란 무엇인가?"에 대한 내용입니다.
목차
1. About Hirschsprung’s disease
2. Aetiology
3. Pathophysiology
4. Symptoms
5. Diagnoses
6. Treatment
본문내용
About Hirschsprung’s disease
.Hirschsprung’s disease (HD)
.Congenital aganglionic megacolon
.Enteric peristaltic movement disorder
.Affects the part of the large intestine
-Most commonly in rectum and sigmoid colon
(short-segment)
-Rare cases in entire colon(includes small intestine)
(long-segment)
.Result of lack of normal nerves (ganglion cells) in submucosal and myenteric plexus
.Affects 1 in 5000 live births
(Lauren and Allecia, 2019)
<중 략>
Aetiology
.Patients with trisomy 21 (Down’s syndrome) are 10 times more likely to have HD compared with the normal population.
.Caused by mutation in RET gene (chromosome 10)
참고 자료
Alan, S., James, L. (2000). Pathology second edition. New York: MOSBY pp133, 271
Alan, S., James, L. and Lan, S. (2009). Core Pathology third edition. China: Elsevier pp272-273
Jonathan, I, L. and Robert O, H. (2013). Initial colonization of the mouse gastrointestinal tract by enteric neural crest. [image] Available at: http://www.researchgate.net/publication/236613891_Enteric_Nervous_System_Development_Migration_Differentiation_and_Disease [Accessed 13 Jan 2020].
J, C, E, Underwood. and S, S, Cross. (2009). General and Systematic pathology fifth edition. China: Churchill Livingstone. Pp96, 378
Kirandeep, B. (2019). Hirschsprung’s disease. [image] Available at: https://teachmepaediatrics.com/surgery/abdominal/hirschsprungs-disease/ [Accessed 9 Jan 2020].
Lauren, K, W. and Allecia M, W. (2019). Educational Case: Hirschsprung Disease. [online] Available at: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6913048/#!po=25.0000 [Accessed 9 Jan 2020].
Nationwide Children’s Hospital. (1991). Hirschsprung Disease (HD). [online] Available at: https://www.nationwidechildrens.org/conditions/hirschsprung-disease-hd [Accessed 12 Jan 2020].
Vinay, K., Abul K, A., Nelson, F. and Jon, C, A. (2010). Pathologic Basis of Disease. The Gastrointestinal Tract. Eighth edition. New York: Elsevier (17) pp766-767
Vinay, K., Abul, K, A. and Nelson, F. (2005). Robbins and Cotran Pathologic Basis of Disease 7th edition. China: Elsevier (17) pp830-831
압축파일 내 파일목록
Hirschsprung’s disease.pptx
script(2).docx