소개글
Modic changes(Vertebral end-plate changes).
목차
없음
본문내용
요통(LBP)이나 좌골신경통(Sciatica)을 호소하는 많은 환자 중 약 20% 정도만이 명확한 해부병리학적인 원인을 통해 진단할 수 있다. 나머지 80%에 해당하는 환자들에게 있어서 특정한 원인을 찾을 수 없었기에 그에 대한 진단의 필요에 의해 연구가 진행되었다. 1980년대 후반에 들어서서 Modic changes에 대한 의견이 대두되었으며, 이후 발표된 논문들을 통해 LBP와 밀접한 연관이 있음이 밝혀졌다.
참고 자료
1) Kuisma M, Karppinen J, Niinimäki J, Kurunlahti M, Haapea M, Vanharanta H, Tervonen O. A three-year follow-up of lumbar spine endplate (Modic) changes. Spine. 2006 Jul 1;31(15):1714-8.
2) Hanne B. Albert ․ Claus Manniche. Modic changes following lumbar disc herniation. Eur Spine J (2007) 16:977–982
3) I. Braithwaite, J. White, A. Saifuddin, P. Renton, B. A. Taylor. Vertebral end-plate (Modic) changes on lumbar spine MRI: correlation with pain reproduction at lumbar discography. Eur Spine J (1998) 7 :363–368
4) Cynthia K. Peterson, RN, DC, M Med Ed,a B. Kim Humphreys, DC, PhD,b and Tania C. Pringle, DC, PREVALENCE OF MODIC DEGENERATIVE MARROW CHANGES IN THE CERVICAL SPINE. Journal of Manipulative and Physiological Therapeutics. January 2007
5) Fouad Fayad, Marie-Martine Lefevre-Colau, Franc¸ois Rannou, Nathaly Quintero, Alain Nys, Yann Mace, Serge Poiraudeau, Jean Luc Drape, Michel Revel. Relation of inflammatory modic changes to intradiscal steroid injection outcome in chronic low back pain. Eur Spine J (2007) 16:925–931
6) Seiji Ohtori, MD, PhD, Gen Inoue, MD, Toshinori Ito, MD, Takana Koshi, MD, Tomoyuki Ozawa, MD, Hideo Doya, MD, Tomoko Saito, MD, Hideshige Moriya, PhD, MD, and Kazuhisa Takahashi, PhD, MD. Tumor Necrosis Factor-Immunoreactive Cells and PGP 9.5-Immunoreactive Nerve Fibers in Vertebral Endplates of Patients With Discogenic Low Back Pain and Modic Type 1 or Type 2 Changes on MRI. SPINE 2006 Volume 31, Number 9, pp 1026–1031
7) D. Mitra, V. N. Cassar-Pullicino, I. W. Mccall. Longitudinal study of vertebral type-1 end-plate changes on MR of the lumbar spine. Eur Radiol (2004) 14:1574–1581