Blood-Brain Barrier
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- 2009.02.01
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- 2008.08
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소개글
Structural Components and Function Under Physiologic and Pathologic Conditions & Ageing and microvascular disease-systematic review and meta-analysis 에 대한 논문을 정리하고 발표한 세미나자료입니다
목차
Introduction
General background
Ageing and microvascular disease
Material and Method
Result
Discussion
Reference
본문내용
2. Introduction General background
Structural components
Endothelial cell
Brain microvascular endothelial cells (BMVEC)
biological functions
barrier, transport of micronutrients and macronutrients, receptor-mediated signaling, leukocyte trafficking, osmoregulation.
Structural components
Tight junctions (TJ)
TJ proteins
occludin, claudins, zonula occludens (ZO)-1, ZO-2, ZO-3, cingulin, AF6, 7H6
Adherent junctions (AJ)
cadherins, catenins, vinculin, actinin
Junctional adhesion molecules
참고 자료
Blood–brain Barrier: Structural Components and Function Under Physiologic and Pathologic Conditions
Yuri Persidsky, Servio H. Ramirez, James Haorah, Georgette D. Kanmogne
Blood–brain barrier: Ageing and microvascular disease – systematic review and meta-analysis
Andrew J. Farrall, Joanna M. Wardlaw
Division of Clinical Neurosciences, University of Edinburgh, Western General Hospital, Crewe Road, Edinburgh EH4 2XU, UK